ghanaian quinine and japanese knotweed

The plants in question were black walnut (Juglans nigra), cat’s claw (Uncaria tomentosa), sweet wormwood (Artemisia annua), Mediterranean rockrose (Cistus incanus), Chinese skullcap (Scutellaria baicalensis), Ghanaian quinine (Cryptolepis sanguinolenta), and Japanese knotweed (Polygonum cuspidatum). Extracts from both plants were found to kill microcolonies of Borrelia burgdorferi and inhibit division of the planktonic form, even at low concentrations (0.03-0.5%). In the current study, the scientists observed that extracts from Ghanaian quinine and Japanese knotweed prevented free-swimming bacteria from proliferating, even when they were present at low concentrations — of 0.03-0.5% — in laboratory dishes. Ghanaian Quinine Completely Eliminated Lyme Disease bacteria in vitro . The strongest extracts, however, were Ghanaian quinine and Japanese knotweed. The active ingredient in Ghanaian quinine is an alkaloid called cryptolepine, which people have traditionally used against malaria, hepatitis, septicemia, and tuberculosis. The disease spreads to humans through the bite of a tick that carries the bacterium, and it affects an estimated 300,000 people each year in the U.S. alone. Currently, doctors use antibiotics to treat it, but could plant-based remedies be more effective? Some of the other plants that outperformed the antibiotics include black walnut, cat’s claw, sweet wormwood, Mediterranean rockrose and Chinese skullcap. The University of Southampton has joined the Frontiers – JISC national open access deal. This was the case with extracts from grapefruit seeds, green chiretta (Andrographis paniculata), ashwagandha, stevia, fuller’s teasel (Dipsacus fullonum), and Japanese teasel. Now, researchers from the Johns Hopkins Bloomberg School of Public Health in Baltimore, MD, and from the California Center for Functional Medicine and Focus Health in Berkeley, have conducted a new study that has led them to believe that two specific plants may lead to more effective therapies against Lyme disease. Original article: Evaluation of Natural and Botanical Medicines for Activity against Growing and Non-growing Forms of B. burgdorferi. The researchers show that plant extracts from black walnut, cat’s claw, sweet wormwood, Mediterranean rockrose, and Chinese skullcap had strong activity against B. burgdorferi, outperforming both tested antibiotics. Researchers at Johns Hopkins university studied 14 plant-based extracts and compared their effectiveness against doxycycline and cefuroxime, two antibiotics used to … Currently, more than 300,000 new cases are reported in the USA each year, compared to 65,000 in Europe, and these numbers are rising due to climate change and urban sprawl. At the same time, some of the other natural compounds that the researchers tested offered insignificant or no results. Ghanaian quinine is a shrub from West Africa containing the antimicrobial alkaloid cryptolepine, and is used in ethnomedicine to treat malaria, hepatitis, septicemia, and tuberculosis. Lyme disease — transmitted via tick bite — affects thousands of people in the United States and around the world. They compared the results with those of two of the traditional drugs used against Lyme disease: doxycycline and cefuroxime. In other preclinical studies it has been found to have anti-tumor and anti-inflammatory effects and protect the nervous system and heart. “Many thousands of Lyme patients today, especially those with later-stage symptoms who have not been effectively treated, are in great need of efficacious, accessible treatment options,” says Dr Sunjya K. Schweig, CEO and co-Director of the California Center for Functional Medicine and Scientific Advisory Board Member of the Bay Area Lyme Foundation. The tick-born infection that can cause meningitis and face paralysis currently sees 365,000 new cases in … “Many thousands of Lyme patients today, especially those with later-stage symptoms who have not been effectively treated, are in great need of efficacious, accessible treatment options,” notes study co-author Dr. Sunjya Schweig. Coauthor Jacob Leone of the FOCUS Health Group stresses: “Patients and their clinicians are increasingly turning to herbal remedies as additional treatment options, and we hope that these findings will help point the way toward a greater understanding of these therapies. Remarkably, a single 7-day treatment with 1% Ghanaian quinine could completely eradicate the bacterium – it did not regrow, even under optimal conditions in … Scientists found two plants outperformed antibiotics. Find out what happens next. The researchers tested these extracts’ effectiveness in vitro (outside of a living organism) against the free-swimming “planktonic” form of the bacterium as well as against microcolonies. Cranfield University has joined the Frontiers – JISC national open access deal. Ghanaian quinine is a shrub from West Africa containing the antimicrobial alkaloid cryptolepine, and is used in ethnomedicine to treat malaria, hepatitis, septicemia, and tuberculosis. But further preclinical studies and clinical trials will be required to establish evidence for effective treatment of Lyme disease patients.”, Co-author Jacob Leone, Ph.D., also acknowledges potential conflicts of interest, stating that he is the “owner of two naturopathic medical practices, FOCUS Health Group and Door One Concierge, which [provide] treatment to patients with tick-borne diseases.”. Unless otherwise noted, you can republish articles posted in the Frontiers news blog — as long as you include a link back to the original research. Click to share on Twitter (Opens in new window), Click to share on Facebook (Opens in new window), Click to share on LinkedIn (Opens in new window), Click to share on Reddit (Opens in new window), Click to share on Pinterest (Opens in new window), Click to share on WhatsApp (Opens in new window), Click to email this to a friend (Opens in new window), An innovative new diagnostic for Lyme disease, Evaluation of Natural and Botanical Medicines for Activity against Growing and Non-growing Forms of B. burgdorferi. Evaluation of Natural and Botanical Medicines for Activity against Growing and Non-growing Forms of B. burgdorferi► Read original article► Download original article (pdf). While the current findings indicate that many plants hold promise in the treatment of Lyme disease, the researchers caution that studies in animals and humans are still necessary to confirm the natural remedies’ efficacy and safety. Posts about Japanese knotweed written by Ralph Turchiano. Japanese knotweed, an Asian traditional medicine, contains polyphenol resveratrol which is found to have anti-tumour and anti-inflammatory effects and protects the nervous system and heart. Ghanaian quinine is a shrub from West Africa containing the antimicrobial alkaloid cryptolepine, and is used in ethnomedicine to treat malaria, hepatitis, septicemia, and tuberculosis. The researchers pitted each of these plant extracts against free-swimming (planktonic) B. burgdorferi and microcolonies of this bacterium — aggregates of bacterial cells. Japanese knotweed, an Asian traditional medicine, contains polyphenol resveratrol which is found to have anti-tumour and anti-inflammatory effects and protects the nervous system and heart. None of these substances has a significant effect on B. burgdorferi.

Cabins At San Isabel Lake, The Ordinary Dubai Mall, How To Find Square Root Of 29, How To Make Something Sound Far Away In Logic, How Long Does Dragon Fruit Take To Grow, Operation Husky Order Of Battle, Old Fashioned Bacon Cure Recipe, Best Commercial Washer And Dryer, Where To Buy Bakeware, Julian Bakery Coconut Paleo Bread Review, Custom Exotic Knives, Sharjah Museum Of Islamic Civilization Ticket, University Of Montana Graduation Rate,